I didn't really know the difference between agonists and antagonists so I looked it up. Essentially, agonists help relax the muscles while the antagonists help contract the muscles. When an agonist produces an action, an antragonist opposes the action. An antagonist blocks the response of a drug, while an agonist works with it. An antagonist blocks the action of a neurotransmitter. So pretty much an antagonist blocks everything, while an agonist goes along with whatever is happening.
http://www.differencebetween.net/science/difference-between-agonist-and-antagonist/
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